HEREDITARY GINGIVAL FIBROMATOSIS PDF

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Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. HGF is characterized as a . Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported . Hereditary gingival fibromatosis can occur as an isolated. Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. This report shows a case of.

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Araiche M, Brode H.

Hereditary gingival fibromatosis

In both cases it was found that on eliminating the gingival fibrosis, eruption proceeded physiologically. There are very few ways to test a patient for HGF. Inflammations, tumors, and cysts can also present themselves as gingival enlargements [ 1 ].

WB Saunders Co; The HGF has a variable clinical presentation. Autosomal dominant gingival fibromatosis Autosomal dominant gingival hyperplasia Hereditary gingival hyperplasia Prevalence: The gingival enlargement may occur alone or in combination of other symptoms as part of a syndrome.

HGF may also be caused by unwanted side effects of pharmacological agents like phenytoinciclosporinand some calcium-channel blockers, meaning HGF is a disease that can be drug-induced. Through review of literature revealed that HGF is usually an autosomal dominant condition, however the recessive forms are also reported. Chronic periodontitis Localized aggressive periodontitis Generalized aggressive periodontitis Periodontitis as a manifestation of systemic disease Periodontosis Necrotizing periodontal diseases Abscesses of the periodontium Combined periodontic-endodontic lesions.

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It appears that the human gingival fibroblasts from hereditary fibromatosis tissue have characteristics of permanently activated fibroblasts. Clinical examination showed persistence of the primary incisors, no eruption of the permanent incisors and lack of lip closure. The documents contained in this web site are presented for information purposes only. Fifteen months later, with regular follow-up visits every three months, the patient showed eruption progress, possibly encouraged by the gingival tissue removal Fig.

Hereditary gingival fibromatosis and growth retardation. From Wikipedia, the free encyclopedia. A Lack of lip closure; B Parallel profile radiograph showing gingiva and bone crest relation; C Intrasurgical view of external bevel incision gingivectomy; D Intraoral view 24 months after surgery. Miller M, Truhe T. The underlying avascular stroma is almost entirely made fibomatosis of dense collagen bundles with only few fibroblasts.

Author information Article notes Copyright and License information Disclaimer. The mass was exuberant in mandibular anterior region obliterating the chin area and submental region [ Figure 4 ].

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It presents an autosomal dominant inheritance pattern although its penetrance and expressivity are variable. Post-surgical healing was uneventful.

Case Reports in Dentistry

Miller M, Truhe T. J Clin Exp Dent. However, no definite linkage has been established. A family pedigree of four generations.

Hereditary gingival fibromatosis: Characteristics and treatment approach

Hereditary gingival fibromatosis in a family of Zimmerman-Laband syndrome. After discussing the treatment possibilities with the patient and her parents, the decision was made to wait until growth potential decreases following the adolescent growth spurt and to fibromatoosis the problem with orthognathic surgery. Some researchers suggest that HGF is transmitted as a Mendelian trait since both autosomal dominant and autosomal recessive transmission has been reported since the early s.

A systematic review ; Recurrence is a gigival feature over varying periods. Profile view of the patient showing lip incompetency at rest. Am J Hum Gen. Gingival overgrowth in children: Buitrago-Vera2 Francisco M.

Hart, Yingze Zhang, Michael C.